Laajuus: 5

Aikataulu: 10.09.2018 - 18.10.2018

Opetusperiodi (voimassa 01.08.2018-31.07.2020): 

I

 

Osaamistavoitteet (voimassa 01.08.2018-31.07.2020): 

After the course the student will be able to evaluate and design an asymmetric synthesis for a moderately complex target molecule. The student will be able to evaluate the practical applicability of different strategies (stoichiometric vs catalytic; internal, external vs relayed asymmetric induction). The course will emphasize the synthetic applications to natural products and medicinal chemistry.

The student will have deeper understanding on natural products (secondary metabolites), their structures, occurrence, significance, classification, and biosynthesis.

Sisältö (voimassa 01.08.2018-31.07.2020): 

Asymmetric synthesis: classification, reaction types, mechanisms. Methods for determining enantiopurity; general methods for asymmetric induction. Reactions of carbonyl compounds and olefins.

Natural products classified according to the classes: their occurrence, biosynthesis and synthesis: sugars, amino acids, nucleic acids, polyketides, terpenes, alkaloids.

Toteutus, työmuodot ja arvosteluperusteet (voimassa 01.08.2018-31.07.2020): 

Lectures, seminar presentation

Työmäärä toteutustavoittain (voimassa 01.08.2018-31.07.2020): 

Lectures 24 h
Seminars 8 h
Home problem solving 20 h
Independent homework 70 h

Oppimateriaali (voimassa 01.08.2018-31.07.2020): 

Koskinen, Asymmetric Synthesis of Natural Products, Wiley & Sons, 2012.

Korvaavuudet (voimassa 01.08.2018-31.07.2020): 

CHEM-E4245 Natural Product Chemistry or CHEM-E4125 Asymmetric Synthesis

Esitiedot (voimassa 01.08.2018-31.07.2020): 

CHEM-E4195 Selectivity in Organic Synthesis or equivalent

Arvosteluasteikko (voimassa 01.08.2018-31.07.2020): 

Fail, 1 – 5

Ilmoittautuminen (voimassa 01.08.2018-31.07.2020): 

WebOodi

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Ilmoittautuminen ja lisätiedot