Credits: 5
Schedule: 01.03.2019 - 09.04.2019
Teacher in charge (valid 01.08.2018-31.07.2020):
Jan Deska
Teaching Period (valid 01.08.2018-31.07.2020):
IV
Learning Outcomes (valid 01.08.2018-31.07.2020):
After the course the student will have deeper understanding on
1. basic biosynthetic principles
2. mechanisms of enzymatic activation
3. biocatalysis in synthesis
4. semi- and mutasynthesis
5. biomimetic organocatalysis
Content (valid 01.08.2018-31.07.2020):
The knowledge of the principle activation mechanisms in biosynthesis helps us to exploit enzymatic catalysts in organic synthesis. This course will provide a brief introduction into the activation modes of enzymes and discuss opportunities and limitations for synthetic chemistry. Furthermore, the course aims to directly connect features of natural catalysts with the rational development of small molecule analogues as found in modern organocatalysis.
Assessment Methods and Criteria (valid 01.08.2018-31.07.2020):
Lectures, problem sessions, learning diary; seminar presentation
Workload (valid 01.08.2018-31.07.2020):
Lectures 24 h
Seminars 8 h
Home problem solving 20 h
Independent homework 80 h
Study Material (valid 01.08.2018-31.07.2020):
All material is provided during the course. Additional information can be found e.g. in Faber: Biotransformations in Organic Chemistry, Springer; Berkessel, Gröger, Asymmetric Organocatalysis, Wiley-VCH
Course Homepage (valid 01.08.2018-31.07.2020):
https://mycourses.aalto.fi/course/search.php?search=CHEM-E8105
Grading Scale (valid 01.08.2018-31.07.2020):
Fail, 1 – 5
Registration for Courses (valid 01.08.2018-31.07.2020):
WebOodi
- Teacher: Deska Jan