Please note! Course description is confirmed for two academic years, which means that in general, e.g. Learning outcomes, assessment methods and key content stays unchanged. However, via course syllabus, it is possible to specify or change the course execution in each realization of the course, such as how the contact sessions are organized, assessment methods weighted or materials used.

LEARNING OUTCOMES

After the course the students will be able to:

  • Appreciate the different levels of biological organization, from molecules to cells
  • Understand the biological processes critical for cellular functioning
  • Can integrate the different processes into the proper cellular context
  • asses the function of regulatory pathways and networks at the cellular level
  • Describe the general principles of gene organization and expression
  • critically analyze experimental data

Credits: 5

Schedule: 30.10.2018 - 12.12.2018

Teacher in charge (valid 01.08.2020-31.07.2022): Alexander Frey

Teacher in charge (applies in this implementation): Alexander Frey

Contact information for the course (applies in this implementation):

CEFR level (applies in this implementation):

Language of instruction and studies (valid 01.08.2020-31.07.2022):

Teaching language: English

Languages of study attainment: English

CONTENT, ASSESSMENT AND WORKLOAD

Content
  • Valid 01.08.2020-31.07.2022:

    The course aims at providing the understanding of essential cellular processes (DNA replication, gene expression, protein targeting and transport, protein modification, membrane transport, secretion and endocytosis, cell signaling, regulation of cell death, cell cycle). The course focuses on eukaryotic organisms.

Assessment Methods and Criteria
  • Valid 01.08.2020-31.07.2022:

    Examination and assignments

  • Applies in this implementation:

    Course grading is based on the assignments (25%) and examination (75%).

Workload
  • Valid 01.08.2020-31.07.2022:

    Total 135 h
    Lectures 24 h
    Assignments 40 h
    Self-study 67 h
    Exam 4 h

  • Applies in this implementation:

    The course requires substantial amount of reading for solving the assignments (27 hours) and preparing for the examination (Self-study 80 hours). For best success, studying for the exam should go in parallel with the course lectures. The reading materials is too comprehensive to be read over a weekend.

DETAILS

Study Material
  • Valid 01.08.2020-31.07.2022:

    Molecular Biology of the Cell, 6th edition, Garland Sciences

  • Applies in this implementation:

    The official course text book is: Molecular biology of the cell / Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter, 6th edition, Published: Garland Science, New York, 2014. A detailed list of the topics selected for the course can be found on MyCourses. It shows the chapters and book sections which are covered in the course.

    An older edition, the 4th edition is available on-line: at http://www.ncbi.nlm.nih.gov/books/NBK21054/. You can search the book but not browse the book. Be aware that not all topics covered in the course might be dealt with at the same level.

Prerequisites
  • Valid 01.08.2020-31.07.2022:

    The course presupposes basic knowledge and competences in the field of Biosciences, which are in content, scope and quality similar to those offered in CHEM-A1310, CHEM-C2300 and CHEM-C2330

FURTHER INFORMATION

Details on the schedule
  • Applies in this implementation:

    In the course four bigger units are covered and each units is accompanied with assignments. During the course there will be four deadlines for submitting the assignments.

    Part I: Chapters 4 & 5 (DNA,
    Chromosomes,
    Genome, replication, recombination)

    Part II: Chapters 6 & 7 (From DNA to protein, control of gene expression)

    Part III: Chapters 10, 12, and 13 (Membrane structures, Intracellular compartments and protein sorting, Membrane Traffic))

    Part IV: Chapters 15 & 17 (Cell signaling, cell cycle)