Credits: 5

Schedule: 07.01.2020 - 20.02.2020

Teacher in charge (valid 01.08.2018-31.07.2020): 

Markus Linder

Teaching Period (valid 01.08.2018-31.07.2020): 

III

Learning Outcomes (valid 01.08.2018-31.07.2020): 

After the course the student has the ability to:
1. Present the physical basis for the function of biological macromolecules.
2. Describe a broad range of analytical techniques for studying biological molecules and their biophysical behavior.
3. Demonstrate the thermodynamic basis for biological interactions, kinetics, and functions.
4. Understand the use of thermodynamic models for predicting the outcome of biological processes.
5. Apply the above knowledge to food science, medical technology, bioanalytical measurements, biomaterials processing, and bioscience research.

Content (valid 01.08.2018-31.07.2020): 

Protein structure and folding, and evolution. Theoretical and practical aspects of methods for the separation and characterization of biological macromolecules. The processes of sedimentation, diffusion and aggregation. Using calorimetry and analytical techniques to study molecular interactions. A basic understanding of the methods to determine three-dimensional structures of biological macromolecules. The application of thermodynamics in biological systems. The thermodynamic basis for cellular conversion and metabolism. The thermodynamic basis for macromolecular behavior and interactions. Mathematical models to understand interactions, including cooperative effects. Principles and applications of colloid and surface science to biomaterials. The basis of enzyme catalysis.

Assessment Methods and Criteria (valid 01.08.2018-31.07.2020): 

The course consists of lectures and assignments. Individual problem-solving exercises.

Workload (valid 01.08.2018-31.07.2020): 

Total 135h = 5cr

Lectures 24 h

Assignments 24 h

Other independent studying 83 h

Exam 4 h

Study Material (valid 01.08.2018-31.07.2020): 

The Molecules of Life: Physical and Chemical Principles ISBN: 9780815341888: Garland Science: Authors: John Kuriyan, Boyana Konforti, David Wemmer

Course Homepage (valid 01.08.2018-31.07.2020): 

https://mycourses.aalto.fi/course/search.php?search=CHEM-E3150

Prerequisites (valid 01.08.2018-31.07.2020): 

CHEM-E3140 Bioprocess technology, CHEM-E3130 Biolab II, or equivalent

Grading Scale (valid 01.08.2018-31.07.2020): 

Fail, 1 – 5 grading is based on assignments (25%) and exam (75%)

Registration for Courses (valid 01.08.2018-31.07.2020): 

WebOodi

Further Information (valid 01.08.2018-31.07.2020): 

Information markus.linder@aalto.fi

Description

Registration and further information