Credits: 5

Schedule: 04.01.2016 - 18.05.2016

Teaching Period (valid 01.08.2018-31.07.2020): 

III-V (Spring)

Learning Outcomes (valid 01.08.2018-31.07.2020): 

After passing the course the student is able to

  • use the basic mathematical and computational tools needed in the statistical modelling of biomolecular structures and their dynamics.
  • understand the balance of forces determining the structure and dynamics of biomolecules.
  • apply the concepts of  Entropy and Free energy in the analysis of energetics of biomolecules.
  • apply concepts of statistical physics in the chemical and phase equilibria in biological structures.
  • use electrostatic interaction of biomolecules as a tool to analyse the ion flow through membranes and other dynamical phenomena.
  • analyse the role of water as solventin biosystems.
  • take the basic  steps of cross-disciplinary analysis (theory, modelling, experiments)  to understand the biomolecular phenomena.

Content (valid 01.08.2018-31.07.2020): 

  • Fundamentals of biomolecules: Biopolymers (nucleic acids and proteins)
  • Biological liquid crystals (lipids).
  • Structural dynamics of biomolecules and their assemblies and the molecular driving forces.
  • Biological many-body systems.
  • Membrane physics.
  • Binding phenomena.

Assessment Methods and Criteria (valid 01.08.2018-31.07.2020): 

Teaching methods:Lectures and exercises

Requirements, assessment methods and criteria: Active participation in teaching and exercises, exam.

Workload (valid 01.08.2018-31.07.2020): 

  • Lecture: contact teaching 10–11 x 2h
  • Exercises: contact teaching 7–8 x 2h
  • Self-study: lecture materials, book: 40h
  • Self-study: exercises: 50h

Study Material (valid 01.08.2018-31.07.2020): 

  • Rob Phillips et al “Physical biology of the cell”
  • Lecture slides
  • Supplementary material as announced later.

Course Homepage (valid 01.08.2018-31.07.2020):

Prerequisites (valid 01.08.2018-31.07.2020): 

Basics of biophysics and thermodynamics. A biophysics course such as NBE-C2101 Biophysics is strongly recommended.

Grading Scale (valid 01.08.2018-31.07.2020): 

0 to 5