CHEM-E4109 - Modern Methods in Biocatalysis D, 02.03.2021-14.04.2021
This course space end date is set to 14.04.2021 Search Courses: CHEM-E4109
Topic outline
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If you are limited to one particular day (9 participants): please check the topics and register asap
If you are not bound to just one day: please wait until Friday, 26.3. at noon, before you register.
The final seminar presentations of the Modern Methods in Biocatalysis course are scheduled on two individual dates, April 13 (Tuesday, 13.15 - 16.00) and April 14 (Wednesday, 13.15 - 16.00). Please pick a topic and prepare a powerpoint-based talk of around 12 minutes that ought to be followed by a brief discussion of up to 3 minutes.
The goal of the presentation is to create a concise and informative overview on the selected topic. Your audience, all participants in this course, should be on a similar knowledge level so you don't need to start with the absolute basics but design your slides focussing on the actual exciting parts of the work.
I kept the selection rather narrow so that we will get mainly pair presentations. I hope everyone of you finds something that you can get excited about. I'll send out a confirmation message after the pairs have formed so that you know who to get in contact with and who to discuss and prepare the presentation with.
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Please pick one topic on one of the two seminar days from the below mentioned list.
Synthetic applications, methods, enzyme cascades
A1) Biocatalytic manufacture of Islatravir (Science 2019, 366, 1255)
A2) Photo-biocatalytic cyclizations (Nature Chem. 2020, 12, 71)
A3) Vinylation Reactions through Biocascades (ACIE 2015, 54, 10899)
A4) Enzymatic Friedel-Crafts chemistry (ACIE 2017, 56, 7615)
A5) Borrowing Hydrogen Biocatalysis (ACIE 2017, 56, 10491)
Enzyme engineering
B1) Evolution of an enantioselective amine oxidase (JACS 2013, 135, 10863)
B2) Bringing Carbon-Silicon Bonds to Life (Science 2016, 354, 1048)
B3) Sigmatropic Rearrangements Catalyzed by Metalloenzymes (ACIE 2016, 55, 13562)
Biosynthesis, metabolic engineering
C1) From Orange Peel to Polymer Building Blocks (Green Chem 2017, 19, 367)
C2) Cannabinoids from engineered yeast (Nature 2019, 567, 123)
C3) Enzymatic Total Synthesis of Sorbicillinoids (ACIE 2018, 57, 14650)
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