Credits: 5
Schedule: 07.01.2019 - 29.05.2019
Teaching Period (valid 01.08.2018-31.07.2020):
III-V (Spring)
Learning Outcomes (valid 01.08.2018-31.07.2020):
After passing the course the student is able to
- use the basic mathematical and computational tools needed in the statistical modelling of biomolecular structures and their dynamics.
- understand the balance of forces determining the structure and dynamics of biomolecules.
- apply the concepts of Entropy and Free energy in the analysis of energetics of biomolecules.
- apply concepts of statistical physics in the chemical and phase equilibria in biological structures.
- use electrostatic interaction of biomolecules as a tool to analyse the ion flow through membranes and other dynamical phenomena.
- analyse the role of water as solventin biosystems.
- take the basic steps of cross-disciplinary analysis (theory, modelling, experiments) to understand the biomolecular phenomena.
Content (valid 01.08.2018-31.07.2020):
- Fundamentals of biomolecules: Biopolymers (nucleic acids and proteins)
- Biological liquid crystals (lipids).
- Structural dynamics of biomolecules and their assemblies and the molecular driving forces.
- Biological many-body systems.
- Membrane physics.
- Binding phenomena.
Assessment Methods and Criteria (valid 01.08.2018-31.07.2020):
Teaching methods:Lectures and exercises
Requirements, assessment methods and criteria: Active participation in teaching and exercises, exam.
Workload (valid 01.08.2018-31.07.2020):
- Lecture: contact teaching 10–11 x 2h
- Exercises: contact teaching 7–8 x 2h
- Self-study: lecture materials, book: 40h
- Self-study: exercises: 50h
Study Material (valid 01.08.2018-31.07.2020):
- Rob Phillips et al “Physical biology of the cell”
- Lecture slides
- Supplementary material as announced later.
Course Homepage (valid 01.08.2018-31.07.2020):
https://mycourses.aalto.fi/course/search.php?search=NBE-E4100
Prerequisites (valid 01.08.2018-31.07.2020):
Basics of biophysics and thermodynamics. A biophysics course such as NBE-C2101 Biophysics is strongly recommended.
Grading Scale (valid 01.08.2018-31.07.2020):
0 to 5
- Teacher: Kuzyk Anton