Please note! Course description is confirmed for two academic years, which means that in general, e.g. Learning outcomes, assessment methods and key content stays unchanged. However, via course syllabus, it is possible to specify or change the course execution in each realization of the course, such as how the contact sessions are organized, assessment methods weighted or materials used.

LEARNING OUTCOMES

After completing the course the student will be able to:

  1. Describe biotechnology as an industrial sector and products and methods thereof, including applications in different fields and challenges and opportunities of industrial biotechnology
  2. Present transition phenomena in bioprocesses (matter and energy-) qualitatively and quantitatively and estimations of the behavior of biological components (cells, proteins, substrates, products, enzymes) under process conditions
  3. Identity the aseptic requirements in equipment- and process design and applications thereof
  4. Present the concept of joining unit operations into bioprocesses and identify phenomena thereof and factors influencing such phenomena
  5. Formulate basic process models for cell and enzymatic processes based on matter- and energy balance and differential equations
  6. Name key variables of bioprocesses and describe the measuring technologies thereof as well as mathematic solutions and basics of process controls

Credits: 5

Schedule: 02.03.2021 - 11.05.2021

Teacher in charge (valid 01.08.2020-31.07.2022): Sandip Bankar, Tero Eerikäinen

Teacher in charge (applies in this implementation): Tero Eerikäinen

Contact information for the course (valid 28.01.2021-21.12.2112):

tero.eerikainen@aalto.fi

CEFR level (applies in this implementation):

Language of instruction and studies (valid 01.08.2020-31.07.2022):

Teaching language: English

Languages of study attainment: Finnish, Swedish, English

CONTENT, ASSESSMENT AND WORKLOAD

Content
  • Valid 01.08.2020-31.07.2022:

    A basic course in Bioprocess technology with focus on:

    Cells: function in reactors, kinetics of growth and yield, kinetics and qantification, dynamic phenomena, practical applications of processes and basic mathematics thereof, basic of metabolism from a systemic point of view

    Enzymes: function in reactors (homogeneous catalysis), thermodynamics of reactions, mass balance, kinetics, immobilized enzymes and mass transfer of reactions, coenzymes and regeneration, inactivation and kinetics thereof.

    (Bio)reactors: typical solutions, transfer phenomena, aseptics in reaction design, methods for measurements and control

    Processes: basics of typical process operations, use of matter and energy balances, bipological factors to be considered with reference to process design

    Basics of phenomena and mathematic modeling of operations and processes with specific focus on biological components.

  • Applies in this implementation:

    Lectures and exercises are held in Zoom or in videos. MyCourses quiz calculations are related to each calculation exercise and lectures.

Assessment Methods and Criteria
  • Valid 01.08.2020-31.07.2022:

    The course includes lectures and exercises.  Students have calculation-assignments and carry out given assignments independently or in a group. Grading is based on independent assignments completed during the course and course examination.

Workload
  • Valid 01.08.2020-31.07.2022:

    5 cr = 135h
    Contact hours (32h):

    - Lectures 8 x 2 ( 2 x weekly) = 16h 

    - Calculation exercises  8 x 2 h  (2 x weekly) = 16 h

    Student Independent work (103 h)

    - Homework 20 h
     - Exam 4 h
    - Independent study 79 h

DETAILS

Study Material
  • Valid 01.08.2020-31.07.2022:

    Electronic book: Doran M. Bioprocess Engineering Principles 2 Ed. (2013)

Substitutes for Courses
  • Valid 01.08.2020-31.07.2022:

    KE-70.2500

Prerequisites
  • Valid 01.08.2020-31.07.2022:

    CHEM-C2300

     

SDG: Sustainable Development Goals

    6 Clean Water and Sanitation

    7 Affordable and Clean Energy

    13 Climate Action