Please note! Course description is confirmed for two academic years, which means that in general, e.g. Learning outcomes, assessment methods and key content stays unchanged. However, via course syllabus, it is possible to specify or change the course execution in each realization of the course, such as how the contact sessions are organized, assessment methods weighted or materials used.


Understand the foundation of enzyme catalysis.

Know and evaluate the potential of different methods for protein engineering.

Be comfortable in drawing chemical reaction mechanisms relevant for biochemistry (“shuffling electrons around”).

Understand selected concepts deeply in order to utilize them to solve future challenges.

Getting used to scientific presentation to peers. 

Search and evaluate state-of-the-art science. 

Credits: 5

Schedule: 08.09.2020 - 25.10.2020

Teacher in charge (valid 01.08.2020-31.07.2022): Silvan Scheller

Teacher in charge (applies in this implementation): Silvan Scheller

Contact information for the course (applies in this implementation):

CEFR level (applies in this implementation):

Language of instruction and studies (valid 01.08.2020-31.07.2022):

Teaching language: English

Languages of study attainment: English


  • Valid 01.08.2020-31.07.2022:

    Basis of enzyme catalysis. Draw reaction coordinates and how to interpret them. Orinciples of how to develop an enzyme inhibitor. Comparison of enzyme catalysis vs. classical catalysis. Enzyme engineering and selected strategies to do this, including  directed evolution. How enzymatic processes can be utilized in a more sustainable way.

    Primary, secondary, tertiary and quaternary protein structure. Chemical properties of all amino acids and their names and abbreviations. Methods to purify a given proteins in the laboratory, procedures for the analysis and sequencing of proteins.



Assessment Methods and Criteria
  • Valid 01.08.2020-31.07.2022:

    The course consists of lectures, exercises and an exam (written and/or oral).

  • Applies in this implementation:

    Individual oral exams via Teams or Zoom (7+7min). 3 days with 30-40 students each. 

  • Valid 01.08.2020-31.07.2022:

    Total 135h = 5cr
    Lectures 24 h

    Exercise sessions 10h
    Assignments or exercises 50 h

    Group work 20 h
    Other independent studying 48 h
    Exam 3 h


Study Material
  • Valid 01.08.2020-31.07.2022:

    To be announced

  • Applies in this implementation:

    This year, we will have the book "Biochemistry Concepts and Connections" by Appling et al. It should be available in electronic form for the students, and there will be online exercises related to it, which will be a large part of the workload. 

Substitutes for Courses
  • Valid 01.08.2020-31.07.2022:

    CHEM-E3180 Concepts in Biochemistry

  • Valid 01.08.2020-31.07.2022:

    CHEM A1310 Biotieteen perusteet, CHEM C2310 Bioprosessitekniikka, or equivalent

SDG: Sustainable Development Goals

    3 Good Health and Well-being

    4 Quality Education

    7 Affordable and Clean Energy

    12 Responsible Production and Consumption


Details on the schedule
  • Applies in this implementation:

    All lectures are compulsory to attend (electronically).