Please note! Course description is confirmed for two academic years (1.8.2018-31.7.2020), which means that in general, e.g. Learning outcomes, assessment methods and key content stays unchanged. However, via course syllabus, it is possible to specify or change the course execution in each realization of the course, such as how the contact sessions are organized, assessment methods weighted or materials used.

LEARNING OUTCOMES

After the course the student has the ability to:
1. Present the physical basis for the function of biological macromolecules.
2. Describe a broad range of analytical techniques for studying biological molecules and their biophysical behavior.
3. Demonstrate the thermodynamic basis for biological interactions, kinetics, and functions.
4. Understand the use of thermodynamic models for predicting the outcome of biological processes.
5. Apply the above knowledge to food science, medical technology, bioanalytical measurements, biomaterials processing, and bioscience research.

Credits: 5

Schedule: 12.01.2021 - 25.02.2021

Teacher in charge (valid 01.08.2020-31.07.2022): Markus Linder

Teacher in charge (applies in this implementation): Markus Linder

Contact information for the course (applies in this implementation):

CEFR level (applies in this implementation):

Language of instruction and studies (valid 01.08.2020-31.07.2022):

Teaching language: English

Languages of study attainment: English

CONTENT, ASSESSMENT AND WORKLOAD

Content
  • Valid 01.08.2020-31.07.2022:

    Protein structure and folding, and evolution. Theoretical and practical aspects of methods for the separation and characterization of biological macromolecules. The processes of sedimentation, diffusion and aggregation. Using calorimetry and analytical techniques to study molecular interactions. A basic understanding of the methods to determine three-dimensional structures of biological macromolecules. The application of thermodynamics in biological systems. The thermodynamic basis for cellular conversion and metabolism. The thermodynamic basis for macromolecular behavior and interactions. Mathematical models to understand interactions, including cooperative effects. Principles and applications of colloid and surface science to biomaterials. The basis of enzyme catalysis.

Assessment Methods and Criteria
  • Valid 01.08.2020-31.07.2022:

    The course consists of lectures and assignments. Individual problem-solving exercises.

Workload
  • Valid 01.08.2020-31.07.2022:

    Total 135h = 5cr

    Lectures 24 h

    Assignments 24 h

    Other independent studying 83 h

    Exam 4 h

DETAILS

Study Material
  • Valid 01.08.2020-31.07.2022:

    The Molecules of Life: Physical and Chemical Principles ISBN: 9780815341888: Garland Science: Authors: John Kuriyan, Boyana Konforti, David Wemmer

Prerequisites
  • Valid 01.08.2020-31.07.2022:

    CHEM-E3140 Bioprocess technology II, CHEM-E3130 Biolab II, or equivalent

SDG: Sustainable Development Goals

    15 Life on Land

FURTHER INFORMATION

Description

Registration and further information