Please note! Course description is confirmed for two academic years (1.8.2018-31.7.2020), which means that in general, e.g. Learning outcomes, assessment methods and key content stays unchanged. However, via course syllabus, it is possible to specify or change the course execution in each realization of the course, such as how the contact sessions are organized, assessment methods weighted or materials used.


After passing the course the student is able to

  • apply the concepts of Entropy and Free energy in the analysis of energetics of biomolecules and biomolecular assemblies

  • adopt physical models for description of biomolecular systems

  • use basic mathematical and computational tools to describe the behavior of biomolecular structures and their dynamics.

  • understand the balance of forces determining the structure and dynamics of cellular structures.

  • describe experimental methods used for investigation of molecular processes in biological systems.

  • take the basic steps of cross-disciplinary analysis (theory, modelling, experiments) to understand the biomolecular phenomena.

  • interpret recent developments, opportunities, challenges and open questions in the field of molecular biophysics.


Credits: 5

Schedule: 11.01.2021 - 02.06.2021

Teacher in charge (valid 01.08.2020-31.07.2022): Anton Kuzyk

Teacher in charge (applies in this implementation): Anton Kuzyk

Contact information for the course (applies in this implementation):

CEFR level (applies in this implementation):

Language of instruction and studies (valid 01.08.2020-31.07.2022):

Teaching language: English

Languages of study attainment: English


  • Valid 01.08.2020-31.07.2022:

    • Fundamentals of biomolecules: Biopolymers (nucleic acids and proteins)

    • Biological liquid crystals (lipid bilayers)

    • Membrane physics

    • Binding phenomena

    • Diffusion and transport

    • Structural dynamics of biomolecules and their assemblies and the molecular driving forces

    • Molecular machines.

Assessment Methods and Criteria
  • Valid 01.08.2020-31.07.2022:

    Teaching methods:Lectures and exercises

    Requirements, assessment methods and criteria: Active participation in teaching and exercises, exam.

  • Valid 01.08.2020-31.07.2022:

    • Lecture: contact teaching 12 x 2h

    • Exercises: contact teaching 11 x 2h

    • Self-study: lecture materials, book: 36h
    • Self-study: exercises: 44h

    • exam and exam preparation: 9


Study Material
  • Valid 01.08.2020-31.07.2022:

    • Rob Phillips et al Physical biology of the cell
    • Lecture slides
    • Supplementary material as announced later.

  • Valid 01.08.2020-31.07.2022:

    Basics of biophysics and thermodynamics. A biophysics course such as NBE-C2101 Biophysics is strongly recommended.



Registration and further information