Please note! Course description is confirmed for two academic years, which means that in general, e.g. Learning outcomes, assessment methods and key content stays unchanged. However, via course syllabus, it is possible to specify or change the course execution in each realization of the course, such as how the contact sessions are organized, assessment methods weighted or materials used.

LEARNING OUTCOMES

After completing the course the student will be able to:

  1. Describe biotechnology as an industrial sector and products and methods thereof, including applications in different fields and challenges and opportunities of industrial biotechnology
  2. Present transition phenomena in bioprocesses (matter and energy-) qualitatively and quantitatively and estimations of the behavior of biological components (cells, proteins, substrates, products, enzymes) under process conditions
  3. Identity the aseptic requirements in equipment- and process design and applications thereof
  4. Present the concept of joining unit operations into bioprocesses and identify phenomena thereof and factors influencing such phenomena
  5. Formulate basic process models for cell and enzymatic processes based on matter- and energy balance and differential equations
  6. Name key variables of bioprocesses and describe the measuring technologies thereof as well as mathematic solutions and basics of process controls

Credits: 5

Schedule: 01.03.2022 - 10.05.2022

Teacher in charge (valid for whole curriculum period):

Teacher in charge (applies in this implementation): Tero Eerikäinen

Contact information for the course (applies in this implementation):

CEFR level (valid for whole curriculum period):

Language of instruction and studies (applies in this implementation):

Teaching language: English. Languages of study attainment: English, Finnish

CONTENT, ASSESSMENT AND WORKLOAD

Content
  • valid for whole curriculum period:

    A basic course in Bioprocess technology with focus on:

    Cells: function in reactors, kinetics of growth and yield, kinetics and qantification, dynamic phenomena, practical applications of processes and basic mathematics thereof, basic of metabolism from a systemic point of view

    Enzymes: function in reactors (homogeneous catalysis), thermodynamics of reactions, mass balance, kinetics, immobilized enzymes and mass transfer of reactions, coenzymes and regeneration, inactivation and kinetics thereof.

    (Bio)reactors: typical solutions, transfer phenomena, aseptics in reaction design, methods for measurements and control

    Processes: basics of typical process operations, use of matter and energy balances, bipological factors to be considered with reference to process design

    Basics of phenomena and mathematic modeling of operations and processes with specific focus on biological components.

Assessment Methods and Criteria
  • valid for whole curriculum period:

    The course includes lectures and exercises.  Students have calculation-assignments and carry out given assignments independently. Grading is based on independent assignments completed during the course and course examination.

Workload
  • valid for whole curriculum period:

    5 cr = 135h
    Contact hours (32h):

    - Lectures 8 x 2 ( 2 x weekly) = 16h 

    - Calculation exercises  8 x 2 h  (2 x weekly) = 16 h

    Student Independent work (103 h)

    - Homework 20 h
     - Exam 4 h
    - Independent study 79 h

DETAILS

Study Material
  • valid for whole curriculum period:

    Electronic book: Doran M. Bioprocess Engineering Principles 2 Ed. (2013)

Substitutes for Courses
Prerequisites
SDG: Sustainable Development Goals

    6 Clean Water and Sanitation

    7 Affordable and Clean Energy

    13 Climate Action

FURTHER INFORMATION

Further Information
  • valid for whole curriculum period:

    Max. 100 students. Students on Aalto's "Bioproducts" and "Chemical Engineering and Processes" major, as well as English Chemical Engineering major. The rest of the students are enrolled in the order of enrollment.

    Teaching Period:

    2020-2021 Spring IV-V

    2021-2022 Spring IV-V

    Course Homepage: https://mycourses.aalto.fi/course/search.php?search=CHEM-C2310

    Registration for Courses: In the academic year 2021-2022, registration for courses will take place on Sisu (sisu.aalto.fi) instead of WebOodi.

    Sisu