CHEM-E4295 - Asymmetric Synthesis of Natural Products, Lecture, 13.9.2021-21.10.2021

Please note! Course description is confirmed for two academic years, which means that in general, e.g. Learning outcomes, assessment methods and key content stays unchanged. However, via course syllabus, it is possible to specify or change the course execution in each realization of the course, such as how the contact sessions are organized, assessment methods weighted or materials used.

LEARNING OUTCOMES

After the course the student will have deeper understanding on natural products (secondary metabolites), their structures, occurrence, significance, classification, and biosynthesis.

The student will gain an understanding on how to evaluate and design an asymmetric synthesis for a moderately complex target molecule. The course will emphasize the synthetic applications to natural products and medicinal chemistry.

 

Credits: 5

Schedule: 13.09.2021 - 21.10.2021

Teacher in charge (valid for whole curriculum period):

Teacher in charge (applies in this implementation): Ari Koskinen

Contact information for the course (applies in this implementation):

CEFR level (valid for whole curriculum period):

Language of instruction and studies (applies in this implementation):

Teaching language: English. Languages of study attainment: English

CONTENT, ASSESSMENT AND WORKLOAD

Content

  • valid for whole curriculum period:

    Asymmetric synthesis: classification, reaction types, mechanisms. Methods for determining enantiopurity; general methods for asymmetric induction. Reactions of carbonyl compounds and olefins.

    Natural products classified according to the classes: their occurrence, biosynthesis and synthesis: sugars, amino acids, nucleic acids, polyketides, terpenes, alkaloids.

Assessment Methods and Criteria

  • valid for whole curriculum period:

    Lectures, seminar presentation

Workload

  • valid for whole curriculum period:

    Lectures 24 h
    Seminars 8 h
    Home problem solving 20 h
    Independent homework 70 h

DETAILS

Study Material

  • valid for whole curriculum period:

    Koskinen, Asymmetric Synthesis of Natural Products, Wiley & Sons, 2012.

Substitutes for Courses
Prerequisites
SDG: Sustainable Development Goals

    3 Good Health and Well-being

    4 Quality Education

    12 Responsible Production and Consumption

FURTHER INFORMATION

Further Information

  • valid for whole curriculum period:

    Teaching Period:

    2020-2021 Autumn I

    2021-2022 Autumn I

    Course Homepage: https://mycourses.aalto.fi/course/search.php?search=CHEM-E4295

    Registration for Courses: In the academic year 2021-2022, registration for courses will take place on Sisu (sisu.aalto.fi) instead of WebOodi.


    This course will be arranged in intensive course mode online: 10 sessions of ca. 1.5 hrs each, within 2-3 days. Dates will be agreed upon with the students after enrolment. Sessions are recorded, but participation in the live lectures is strongly encouraged.

Rules of Conduct - Students´ Rights and Responsibilities (in force from 1 August 2020)

Aalto University Code of Academic Integrity and Handling Violations Thereof