LEARNING OUTCOMES
Understand the foundation of enzyme catalysis.
Know and evaluate the potential of different methods for protein engineering.
Be comfortable in drawing chemical reaction mechanisms relevant for biochemistry ( shuffling electrons around ).
Understand selected concepts deeply in order to utilize them to solve future challenges.
Getting used to scientific presentation to peers.
Search and evaluate state-of-the-art science.
Credits: 5
Schedule: 14.09.2021 - 29.10.2021
Teacher in charge (valid for whole curriculum period):
Teacher in charge (applies in this implementation): Silvan Scheller, Juha Oksa
Contact information for the course (applies in this implementation):
CEFR level (valid for whole curriculum period):
Language of instruction and studies (applies in this implementation):
Teaching language: English. Languages of study attainment: English
CONTENT, ASSESSMENT AND WORKLOAD
Content
valid for whole curriculum period:
Basis of enzyme catalysis. Draw reaction coordinates and how to interpret them. Orinciples of how to develop an enzyme inhibitor. Comparison of enzyme catalysis vs. classical catalysis. Enzyme engineering and selected strategies to do this, including directed evolution. How enzymatic processes can be utilized in a more sustainable way.
Primary, secondary, tertiary and quaternary protein structure. Chemical properties of all amino acids and their names and abbreviations. Methods to purify a given proteins in the laboratory, procedures for the analysis and sequencing of proteins.
Assessment Methods and Criteria
valid for whole curriculum period:
The course consists of lectures, exercises and an exam (written and/or oral).
Workload
valid for whole curriculum period:
Total 135h = 5cr
Lectures 24 hExercise sessions 10h
Assignments or exercises 50 hGroup work 20 h
Other independent studying 48 h
Exam 3 h
DETAILS
Study Material
valid for whole curriculum period:
To be announced
Substitutes for Courses
valid for whole curriculum period:
Prerequisites
valid for whole curriculum period:
SDG: Sustainable Development Goals
3 Good Health and Well-being
4 Quality Education
7 Affordable and Clean Energy
12 Responsible Production and Consumption
FURTHER INFORMATION
Further Information
valid for whole curriculum period:
Teaching Period:
2020-2021 Autumn I
2021-2022 Autumn I
Course Homepage: https://mycourses.aalto.fi/course/search.php?search=CHEM-C2330
Registration for Courses: In the academic year 2021-2022, registration for courses will take place on Sisu (sisu.aalto.fi) instead of WebOodi.
Sisu