CHEM-E8115 - Cell Factory D, Lecture, 10.1.2023-24.2.2023

Please note! Course description is confirmed for two academic years, which means that in general, e.g. Learning outcomes, assessment methods and key content stays unchanged. However, via course syllabus, it is possible to specify or change the course execution in each realization of the course, such as how the contact sessions are organized, assessment methods weighted or materials used.

LEARNING OUTCOMES

After the course the students should be able to: 

  • know the advantages and disadvantages of the different types of expression hosts
  • choose the optimal expression host for a given product
  • identify rate-limiting steps and know how to overcome them
  • modify the expression system for improved production and/or improved characteristics of the target molecule
  • select appropriate tools and strategies for genetic engineering

Credits: 5

Schedule: 10.01.2023 - 24.02.2023

Teacher in charge (valid for whole curriculum period):

Teacher in charge (applies in this implementation): Alexander Frey

Contact information for the course (applies in this implementation):

CEFR level (valid for whole curriculum period):

Language of instruction and studies (applies in this implementation):

Teaching language: English. Languages of study attainment: English

CONTENT, ASSESSMENT AND WORKLOAD

Content

  • valid for whole curriculum period:

    This course focuses on the exploitation of cellular systems for the production of enzymes, therapeutic proteins, biochemicals and secondary metabolites. It is located at the interface between biochemistry, microbiology, cell biology and metabolic engineering.

    The course aims at the analysis, understanding and recombining of natures molecular building blocks using genetic engineering and molecular breeding technologies. This allows the creation of new expression and production systems, ranging from microbial, plant, insect to animal cells.
    A project work accompanies the lectures where students design a cell factory.

Assessment Methods and Criteria

  • valid for whole curriculum period:

    Fail, 1 – 5; grading is based on examination (60%) and project work (40%)

Workload

  • valid for whole curriculum period:

    Total 135 h 
    Lectures and Seminars 20 to 24 hours
    Project work 50 hours
    Self-study 57 to 61 hours
    Exam 4 hours

DETAILS

Substitutes for Courses
Prerequisites
SDG: Sustainable Development Goals

    3 Good Health and Well-being

    13 Climate Action

FURTHER INFORMATION

Further Information

  • valid for whole curriculum period:

    Teaching Language : English

    Teaching Period : 2022-2023 Spring III
    2023-2024 Spring III

    A course implementation may be cancelled if the number of students enrolled to the course implementation does not meet the required minimum of five students. In the case of cancelled course implementations, the students enrolled to them must be provided with an alternative way of completing the course or be advised to take some other applicable course.

Rules of Conduct - Students´ Rights and Responsibilities (in force from 1 August 2020)

Aalto University Code of Academic Integrity and Handling Violations Thereof