Syllabus

LEARNING OUTCOMES

On successful completion of this course, students should be able to:
IL01 - Analyze the bioprocess development and apply it for commercial interest
IL02 - Construct and interpret the bioprocess parameters in bioreactor
IL03 – Apply different downstream processing steps in bioprocess operation
IL04 - Design a bioprocess starting from fermentation to final purification
IL05 - Present the importance of bioprocess technology to a group of audience and appreciate the importance of group work

Credits: 5

Schedule: 24.10.2022 - 08.12.2022

Teacher in charge (valid for whole curriculum period):

Teacher in charge (applies in this implementation): Emma Master

Contact information for the course (applies in this implementation):

CEFR level (valid for whole curriculum period):

Language of instruction and studies (applies in this implementation):

Teaching language: English. Languages of study attainment: English

CONTENT, ASSESSMENT AND WORKLOAD

Content

• valid for whole curriculum period:

  Industrial importance of Bioprocess Technology, microbial growth and product formation kinetics, process scale up and design, bioreactor operation consideration, mixing in bioreactors, design and control of bioprocess parameters

• applies in this implementation

  This course will cover concepts and techniques relevant to biomanufacturing, including cell cultivation, enzyme production and application, and biochemical synthesis through fermentation. Students will learn how to apply metabolic principles to predict biochemical products and yields, and core principles relevant to industrial enzyme development and use.

  Specific learning outcomes are as follows:

  Lecture 1: Industrial enzymes

  • Use of enzymes in biorefineries
  • Differences of biorefinery feedstocks
  • Challenges in biorefineries

  Lecture 2: Enzyme development

  • Considerations for enzyme production
  • Principles of protein purification
  • Assessment of enzyme performance

  Lecture 3: Impact of metabolic diversity

  • Diversity of microbial catabolism
  • Expression of diverse metabolic activities as redox equations
  • Application of redox expressions to calculate bioproduct yields and catalytic efficiency

  Lecture 4: Wastewater treatment – Basics and principles

  • Principles of coagulation and flocculation
  • Solid-liquid separation by coagulation and flocculation
  • WQQM – Water Quality and Quantity Management
  • Basics of wastewater treatment
  • Physical, chemical and biochemical processes and process combinations
  • Aerobic and anaerobic treatment steps

  Lecture 5: Wastewater treatment – Industrial applications and examples

  • Wastewater treatment step by step
  • Nutrient recycling: N and P
  • Reduction of waste volumes for disposal
  • Energy from waste streams
  • Problems in wastewater treatment
  • Mass flows, mass balances, costs
  
  

Assessment Methods and Criteria

• valid for whole curriculum period:

  Continuous assessment – Problem based learning, after-lecture quiz, learning diary, calculation exercise open book assignment

  No final written examination in this course.

• applies in this implementation

  Evaluation questions will be posted at the end of each lecture; responses much be submitted within one week. 
  

  
  

Workload

• valid for whole curriculum period:

  Teaching methods - Lectures, group work, assignments

• applies in this implementation

  Five course assignments will be issued; one following each lecture. The assignments will have equal weighting on the final grade.
  

DETAILS

Study Material

• applies in this implementation

  Lecture slides will be shared through MyCourses.

  Assessment materials will also be distributed through MyCourses.
  

Substitutes for Courses

• valid for whole curriculum period:

  Substitutes for Courses

Prerequisites

• valid for whole curriculum period:

  Prerequisites

SDG: Sustainable Development Goals

9 Industry, Innovation and Infrastructure

12 Responsible Production and Consumption

15 Life on Land

FURTHER INFORMATION

Further Information

• valid for whole curriculum period:

  Exchange students should send their transcript to the teacher before starting the course.

  Teaching Language : English

  Teaching Period : 2022-2023 Autumn II
  2023-2024 Autumn II

  Enrollment :

  A maximum number of 45 students will be admitted to the course. Degree students will be prioritized, exchange students will be admitted if they fulfill the needed prerequisites and there is space left on the course.

   

  A course implementation may be cancelled if the number of students enrolled to the course implementation does not meet the required minimum of five students. In the case of cancelled course implementations, the students enrolled to them must be provided with an alternative way of completing the course or be advised to take some other applicable course.

Details on the schedule

• applies in this implementation

  The lecture period are on Mondays from 10:15 am  - 12 noon (8.75 hours total)

  Practice exercises are scheduled on November 3 and 10, from 10:15 am  - 12 noon (3.5 hours total)
  

Description