CHEM-E4170 - Advanced Organic Chemistry D, Lecture, 22.10.2024-28.11.2024

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Please note! Course description is confirmed for two academic years, which means that in general, e.g. Learning outcomes, assessment methods and key content stays unchanged. However, via course syllabus, it is possible to specify or change the course execution in each realization of the course, such as how the contact sessions are organized, assessment methods weighted or materials used.

LEARNING OUTCOMES

After the course the student will be able to:

  • Understand and justify chemical reactivity based on molecular orbital theory.
  • Propose curved arrow mechanisms for complex organic reactions.
  • Understand and justify selectivities.
  • Understand stereoelectronic effects and be able to carry out conformational analyses for complex molecules.
  • Solve complex problems collaboratively.

Credits: 5

Schedule: 22.10.2024 - 28.11.2024

Teacher in charge (valid for whole curriculum period):

Teacher in charge (applies in this implementation): Juha Siitonen, Suvi Holmstedt

Contact information for the course (applies in this implementation):

CEFR level (valid for whole curriculum period):

Language of instruction and studies (applies in this implementation):

Teaching language: English. Languages of study attainment: English

CONTENT, ASSESSMENT AND WORKLOAD

Content

  • valid for whole curriculum period:

    Developing a comprehensive understanding of organic structure and reactivity from first principles. Describing complex multi-step organic reactions using curved arrows and molecular orbitals. Using thermodynamic and kinetic arguments to justify chemical reactivity and selectivity. Advanced stereochemistry and conformational analysis of acyclic and cyclic systems.

    After the course a student will have the theoretical tools needed to understand organic chemistry pertaining to e.g. natural product total synthesis, medicinal chemistry, polymer chemistry, biomass chemistry and supramolecular chemistry.

Assessment Methods and Criteria

  • valid for whole curriculum period:

    Homework problems: 50%

    Synthesis plan (credibility, creativity, use of literature): 50%

Workload

  • valid for whole curriculum period:

    5 op = 135 h

    Lectures: 20 h

    Homework problems: 40 h

    Synthesis project: 75 h

DETAILS

Study Material

  • valid for whole curriculum period:

    Course material

    Classics in Total Syntesis 1–3 (KC Nicolaou et. al.)

    Modern Organic Synthesis: An Introduction, 2nd Edition (George S. Zweifel, Michael H. Nantz, Peter Somfai.)

Substitutes for Courses
Prerequisites
SDG: Sustainable Development Goals

    2 Zero Hunger

    3 Good Health and Well-being

    7 Affordable and Clean Energy

    12 Responsible Production and Consumption

    14 Life Below Water

    15 Life on Land

FURTHER INFORMATION

Further Information

  • valid for whole curriculum period:

    Teaching Language: English

    Teaching Period: 2024-2025 Autumn II
    2025-2026 Autumn II

Rules of Conduct - Students´ Rights and Responsibilities (in force from 1 August 2020)

Aalto University Code of Academic Integrity and Handling Violations Thereof