Enrolment options

Please note! Course description is confirmed for two academic years, which means that in general, e.g. Learning outcomes, assessment methods and key content stays unchanged. However, via course syllabus, it is possible to specify or change the course execution in each realization of the course, such as how the contact sessions are organized, assessment methods weighted or materials used.

LEARNING OUTCOMES

After the course the students will be able to:

  1. Utilize public databases and analyze sequence data to search for potential enzymes and to predict enzymatic functionalities.
  2. Assess methods to evaluate related enzyme activities.
  3. Design genetic engineering strategies to modify proteins leading to improved or altered performance or to novel or improved products.
  4. Visualize and analyze the structure-function relationship of enzymes.
  5. Justify strategies for the recombinant production and purification of enzymes from different origin and with different cofactor requirements.
  6. Design a scientific or a research and development project relating to the application of enzymes to address academic, industrial, or societal problems.
  7. Critically analyze and assess relevant literature and apply it to solve challenges in enzyme design.
  8. Report and discuss scientific results in oral and written form.

Credits: 5

Schedule: 26.02.2025 - 04.04.2025

Teacher in charge (valid for whole curriculum period):

Teacher in charge (applies in this implementation): Mäkelä

Contact information for the course (applies in this implementation):

Miia Mäkelä, miia.makela@aalto.fi

Christina Lyra, christina.lyra@aalto.fi


CEFR level (valid for whole curriculum period):

Language of instruction and studies (applies in this implementation):

Teaching language: English. Languages of study attainment: English

CONTENT, ASSESSMENT AND WORKLOAD

Content
  • valid for whole curriculum period:

    The course covers aspects which are relevant to both academic research and industrial applications revolving around enzymes. Topics covered include enzyme production, methods to assess enzyme activities and kinetics, as well as in-depth understanding of the current methods used to design and engineer proteins. The learnings will be applied to relevant case studies to illustrate the diversity of enzyme applications and to analyze the suitability of the varying methods used to select, design and produce enzymes.

Assessment Methods and Criteria
  • valid for whole curriculum period:

    Fail, 1 – 5; grading is based on assignments

Workload
  • valid for whole curriculum period:

    The course contains lectures, assignments, and self-study.

DETAILS

Substitutes for Courses
Prerequisites

FURTHER INFORMATION

Further Information
  • valid for whole curriculum period:

    Teaching Language: English

    Teaching Period: 2024-2025 Spring IV
    2025-2026 Spring IV

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