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CHEM-E8115 - Cell Factory, 09.01.2019-22.02.2019

This course space end date is set to 22.02.2019   Search Courses: CHEM-E8115

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Part II: Expression of recombinant proteins: limitations and engineering strategies

Completion requirements

The focus of part II is on recombinant protein production and how productivity can be increased or new products be generated. We'll revisit selected cellular processes such as protein N-glycosylation, protein folding, secretion and see how these processes can be modified and improved.



    • Baneyx2004.pdf Baneyx2004.pdf
    • De Pourcq et al. - 2010 - Engineering of glycosylation in yeast and other fungi current state and perspectives.pdf De Pourcq et al. - 2010 - Engineering of glycosylation in yeast and other fungi current state and perspectives.pdf
    • Gasser et al. - 2008 - Protein folding and conformational stress in microbial cells producing recombinant proteins a host comparative overview.pdf Gasser et al. - 2008 - Protein folding and conformational stress in microbial cells producing recombinant proteins a host comparative overview.pdf
    • Idiris et al. - 2010 - Engineering of protein secretion in yeast strategies and impact on protein production.pdf Idiris et al. - 2010 - Engineering of protein secretion in yeast strategies and impact on protein production.pdf
    • Lecture5_glycosylation.pdf Lecture5_glycosylation.pdf
    • Lecture6_engineering cell factories_eukaryotes.pdf Lecture6_engineering cell factories_eukaryotes.pdf
    • Lecture7_engineering cell factories_prokaryotes.pdf Lecture7_engineering cell factories_prokaryotes.pdf
    • Schröder_2008.pdf Schröder_2008.pdf
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◄ Part I: An overview of production systems and engineering tools:
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Part III: Metabolic engineering ►
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